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Weight Loss Medications

Snoring and Sleep Services performed at ENTACC

Weight loss drugs, particularly those containing Tirzepatide (Zepbound, Mounjaro), have shown promise in improving obstructive sleep apnea (OSA) in individuals with obesity. Studies have demonstrated that Tirzepatide reduces the severity of sleep apnea, and the FDA has even approved Zepbound specifically for the treatment of moderate to severe OSA in adults with obesity, alongside diet and exercise.

Here's a more detailed explanation:

Weight Loss and OSA:

Obesity is a major risk factor for OSA, and weight loss can significantly reduce the severity of the condition. 

Tirzepatide and OSA:

Studies have found that Tirzepatide, a medication used for weight loss and type 2 diabetes, can also improve OSA symptoms, including reducing breathing disruptions and increasing the number of patients who can potentially discontinue CPAP therapy.

FDA Approval:

The FDA has approved Zepbound (Tirzepatide) for treating moderate to severe OSA in adults with obesity.

Mechanism of Action:

Tirzepatide works by stimulating the release of hormones that help reduce appetite and promote weight loss, which in turn can alleviate the symptoms of OSA. 

Important Considerations:

While weight loss drugs show promise for OSA, it's crucial to remember that they are not a standalone solution. They should be used in conjunction with a reduced-calorie diet, increased physical activity, and potentially other therapies like CPAP. 

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